Write the clinical question use PICO (using the power point of lecture 2) to know how to write the clinical question, Based on the case study provided (find a Randomized Controled Trial paper, apply the appraisal steps on it (uploaded appraisal sheet) 2.
Write the clinical question use PICO (using the power point of lecture 2) to know how to write the clinical question, Based on the case study provided (find a Randomized Controled Trial paper, apply the appraisal steps on it (uploaded appraisal sheet) 2.
Find the best evidence (do not use Systematic review) use RCT (randomized control trial) Indicate your search strategy (using finding evidence document) please include capture screen shots from where you got the reference (RCT). 3. Evaluate the evidence (using critical appraisal sheet) by answering the questions on that sheet (please use the same sheet and write the answers from that paper you choose-RCT (Randomised Control Trial)- and write your answer on the same sheet).
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THERAPY STUDY:
Are the results of the trial valid? (Internal Validity)
What question did the study ask?
Patients –
Intervention –
Comparison –
Outcome(s) –
Did the trial address a clear, focused, and valid question?
Was the assignment of patients to treatments randomised?
What is best? Where do I find the information?
Centralised computer randomisation is ideal and often used in multi-centred trials. Smaller trials may use an independent person (e.g, the hospital pharmacy) to “police” the randomization. The Methods should tell you how patients were allocated to groups and whether or not randomisation was concealed.
This paper: Yes No Unclear
Comment:
2. Were the groups similar at the start of the trial?
What is best? Where do I find the information?
If the randomisation process worked (that is, achieved comparable groups) the groups should be similar. The more similar the groups the better it is.
There should be some indication of whether differences between groups are statistically significant (ie. p values).
The Results should have a table of “Baseline Characteristics” comparing the randomized groups on a number of variables that could affect the outcome (ie. age, risk factors etc). If not, there may be a description of group similarity in the first paragraphs of the Results section.
This paper: Yes No Unclear
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