Explain five different ways of describing the natural history of a disease.1.Describe the phases of testing new drugs in the United States. Why does it take so long for a new drug to come to market in the U.S.?

Explain five different ways of describing the natural history of a disease.1.Describe the phases of testing new drugs in the United States. Why does it take so long for a new drug to come to market in the U.S.?

2.Describe the important elements of randomized trials, explaining why each element is necessary for a successful study.

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3. Explain five different ways of describing the natural history of a disease. Briefly explain why each approach might be utilized.

4. Discuss sample sizes, Type I Errors, Type II Errors, power, generalizability, and internal validity. Provide an example for each of these.

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