Infectious diseases remain one of the leading causes of death due to antibiotic resistant microorganisms. The frequency of resistance in microbial pathogens continues to grow at an alarming rate throughout the world (Schmitz et al., 1999). Decreased efficacy and resistance of pathogens to antibiotics has necessitated development of new alternatives (Ravikumar et al., 2010).

Infectious diseases remain one of the leading causes of death due to antibiotic resistant microorganisms. The frequency of resistance in microbial pathogens continues to grow at an alarming rate throughout the world (Schmitz et al., 1999). Decreased efficacy and resistance of pathogens to antibiotics has necessitated development of new alternatives (Ravikumar et al., 2010).

To overcome these problems, the development of effective newer drugs without any side effects is an urgent need. In general, marine plants such as mangroves, seaweeds, sea grasses and marines sponges are extensively studied for antiviral, antiplasmodial, antibacterial, antifungal, hepatoprotective, anti-ulcer properties (Ravikumar et al., 2009&2011).

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Medicinal plant is plant containing substance which can be used for the medication or become precursor of drug synthesis (Sofowora, 1982). Medicinal plant has been source of human health since ancient time, whereas about 60-75% of world populations require plant for carrying health (Farnsworth, 1994; Joy et al., 1998 and Harvey, 2000). Plants and microbes are the main source of natural products (Hayashi et al., 1997; Armaka et al., 1999; Lin et al., 1999a &b and Basso et al., 2005), and consistently become main source of the newest drugs (Harvey, 2000). The drug development from natural sources are based on the bioassay-guided isolation of natural products, due to the traditional uses of local plants (ethnobotanical and ethanopharmacological applications) (Atta-ur-Rahman and Choudhary, 1999).

Seagrasses are submerged marine angiosperms growing abundantly in tidal and sub tidal areas of all seas except in the Polar Regions. Sea grass biomass is used as human food especially by coastal populations (Hemminga and Duarte, 2000). In folk medicine, seagrasses have been used for a variety of remedial purposes, like, fever, skin diseases, muscle pains, wounds and stomach problems etc. (de la Torre-Castro and Rönnbäck, 2004). In India, seagrasses were used as medicine (treatment of heart conditions, seasickness), food (nutritious seeds), fertilizer (nutrient rich biomass) and livestock feed (goats and sheep) (Newmaster et al., 2011). Seeds of Enhalus acoroides are thought to have aphrodisiac and contraceptive properties (Aliño et al., 1990). (12)

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