Reoviruses use double-strand RNA to encode their genome. Why is this a problem for a virus that infe Show more Reoviruses use double-strand RNA to encode their genome.
Reoviruses use double-strand RNA to encode their genome. Why is this a problem for a virus that infe Show more Reoviruses use double-strand RNA to encode their genome.
Why is this a problem for a virus that infects mammalian cells and how does the virus prevent this problem? A. Double-stranded RNA is easy to melt and release the (+) mRNA strand for translation. Reoviruses bring their own RNA gyrase and helicase with them. B. Double-stranded RNA is a potent inducer of the antiviral interferon pathway. Reoviruses maintain their dsRNA genome segments inside of their capsid at all times during the infectious cycle. C. Double-stranded RNA is difficult to melt and release the (+) mRNA strand for translation. Reoviruses bring their own RNA gyrase and helicase with them. D. Double-stranded RNA is a potent inducer of the antiviral interferon pathway. Reoviruses maintain their ssRNA genome segments inside of their capsid at all times during the infectious cycle. E. Double-stranded RNA is a potent repressor of the antiviral interferon pathway. Reoviruses maintain their dsRNA genome segments inside of their capsid at all times during the infectious cycle. Show less
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