The remainder of the paper should present the rationale for one (1) management strategy to show your understanding of the links between the physiology, signs and symptoms and management. Please note, you may not cover renal replacement therapy, intra-aortic balloon counterpulsation or positive pressure ventilation.

Select a complex critical care patient for case study who has multiple organ dysfunction as shown by one or two of the following health conditions • Liver failure • Renal failure • Neurological compromise • Circulatory failure • Endocrine failure • Haematological failure

Write a brief summary of the patient’s major health problem that lead to the requirement for critical care and any significant management provided specific to the problem. This should take no more than one to one and a half pages.

The emphasis for the paper is to show a detailed understanding of the pathophysiology underpinning the patients’ primary problem. You are expected to provide detailed rationale for the clinical signs the patient is showing.

Please note as the patient may have multiple organ dysfunction selecting one area on which to concentrate may assist your writing. You will however be expected to examine the relationship between at least two organ dysfunctions.

The remainder of the paper should present the rationale for one (1) management strategy to show your understanding of the links between the physiology, signs and symptoms and management. Please note, you may not cover renal replacement therapy, intra-aortic balloon counterpulsation or positive pressure ventilation.

Maintain patient confidentiality by assigning the person a pseudonym. No case details are to be included beyond discussing the relevant physiology.

Your introduction should describe how the paper is to be presented and organized. The content of the paper must use a minimum of 15 scholarly references to support your discussion points. The paper will be written in a manner that clearly demonstrates understanding of the related pathophysiology by drawing on recent, research-based literature. Laboratory findings may be discussed if relevant.

Assessment criteria • Selects a patient with the required complex critical care and presents work that shows critical analysis of the selected topic • Comprehensively describes and relates the relevant pathophysiology appropriate to the patient’s clinical condition • Demonstrates critical engagement with the relevant evidence based research • Establishes clear relationships between the physiology and selected management topic • Writes clearly in an appropriate academic style and Harvard reference style.

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