Traumatic Brain Injury (TBI) affects a wide variety of people nationwide. One constant does remain; the human condition suffers, both internally and externally.

Traumatic Brain Injury (TBI) affects a wide variety of people nationwide. One constant does remain; the human condition suffers, both internally and externally.

The proposed study will review current literature and collective research models and data based on neural stem cell transplantation on injured brains and their positive outcomes; as well as, the facilitation of newly implemented procedures for localized drug therapy on their respective injury sites. Studies are primarily collected in controlled laboratory setting and modeled on mice for efficacy of desired treatment protocol as well as the clinical setting being modeled on Projectile Ballistics Brain Injury (PBBI) patients.

Pertinent research questions include: Is there sufficient clinical evidence to support that

the usage of neural progenitor cells expand neurogenesis activity within TBI structures of the

brain? As well as, What are the effects of neural stem cell transplants on endogenous neurogenesis

and neurobehavioral outcomes of PBBI patients? Data analysis was collected by reviewing TBI

literature under different treatment circumstances such as hypothermic, neurodegenerative,

immuno-compromised, behavioral standards, and lastly by quantifying the rate of neural cell

apoptosis within a 6 week period measured at 95% CI (α < p-value = 0.05). Overall the research

hopes to raise awareness of the achievable goals and positive steps that have been affiliated with

this specific type of research methodology.

PROBLEM STATEMENT

The general problem is represented with the figures provided by the CDCP in 2010;

about 2.5 million Emergency Department (ED) cases were associated with TBI; either presented

singly or in combination with another injury here in the United States (CDCP, 2014). TBI was a

diagnosis in more than 280,000 hospitals and of those cases 50,000 ended in death before and

while at the ED (CDCP, 2014). TBI’s rooted issues are based on scientific evidence that out of the

73 institutions currently focused on TBI research, only three are using neural stem cells to

promote neurogenesis in the brain and out of those three institutions, only two have a drug

approved by the FDA that increases glucose activity in injured bregma regions of the brain

(National Institute of Neurological Disorders and Stroke [NINDS], 2016). TBI is a major source

of death and disability here in the US; not only does it account for a large portion of ED care and

attention, treatment procedures and positive outcomes in today’s world of modern day medicine

Explanation & Answer

Our website has a team of professional writers who can help you write any of your homework. They will write your papers from scratch. We also have a team of editors just to make sure all papers are of HIGH QUALITY & PLAGIARISM FREE. To make an Order you only need to click Order Now and we will direct you to our Order Page at Litessays. Then fill Our Order Form with all your assignment instructions. Select your deadline and pay for your paper. You will get it few hours before your set deadline.