WHAT HAPPENS TO A DRUG THAT METABOLIZES QUICKLY IN THE LIVER? Eam: 084086RR – Adverse Reactions/Drug Interactions1. What happens to a drug that metabolizes quickly in the liver?A.
WHAT HAPPENS TO A DRUG THAT METABOLIZES QUICKLY IN THE LIVER?
Eam: 084086RR – Adverse Reactions/Drug Interactions1. What happens to a drug that metabolizes quickly in the liver?A.
Eam: 084086RR – Adverse Reactions/Drug Interactions1. What happens to a drug that metabolizes quickly in the liver?A. It gains in effectiveness and toicity.B. It loses its effect quickly.C. It loses its effect slowly.D. It becomes an inactive alcohol. 2. The following figures indicate the incidence of drug-induced tremors for four drugs: Drug A: 11 percent;Drug B: 9.5 percent; Drug C: 10 percent; Drug D: 2 percent. Which of these drugs causes the highestincidence of tremors?A. Drug DB. Drug CC. Drug AD. Drug B 3. Which of the following adverse drug reactions indicates an impaired production of platelets?A. ThrombocytosisB. AgranulocytosisC. ThrombocytopeniaD. Anemia 4. Which of the following adverse drug effects indicates sleepiness?A. SomnolenceB. PharyngitisC. DyspepsiaD. Hypokinesia 5. Which of the following digestive system effects is the most common adverse reaction seen withnonsteroidal anti-inflammatory drugs (NSAIDs)?A. DiarrheaB. ConstipationC. AnoreiaD. Gastric irritation 6. A patient who is taking carbamazepine (Tegretol) to prevent seizures should not be givenA. codeine.B. acetaminophen.C. phenylbutazone (Butazolidin).D. propoyphene (Darvocet-N). 7. Which of the following drugs should not be given to patients who are taking oral contraceptives?A. ProzacB. Penicillin VKC. AspirinD. Acetaminophen 8. Which of the following adverse drug reactions indicates a greater number of white cells than normal?A. LeukocytosisB. LeukopeniaC. DermatitisD. Hypotension 9. Adverse reactions caused by a drug are also called _______ actions.A. undesirableB. therapeuticC. beneficialD. desirable 10. The description of drug-induced allergies will be found in the adverse-reaction section of a drugmonograph under the categoryA. Endocrine System.B. Special Senses.C. Hematologic Effects.D. Hypersensitivity Reactions. 11. When a drug interacts with warfarin, the drug may cause a dangerous adverse effect byA. causing the withdrawal of warfarin.B. inhibiting the oidative actions of the drug-metabolizing enzyme system.C. enhancing the effect of the anticoagulant.D. increasing the psychomotor impairment of the patient. 12. Which of the following statements about pharmacovigilance is true?A. Physicians and patients are required to make reports about adverse drug reactions to pharmacovigilance centers.B. Only the long-term side effects of medicines are investigated by pharmacovigilance researchers.C. Pharmacovigilance is devoted to detecting, understanding, and preventing adverse effects in patients.D. Pharmacovigilance research takes place before a drug has gone through clinical trials and entered the marketplace. 13. Using alcohol with _______ will cut their lethal dose in half.A. barbituratesB. narcoticsC. tranquilizersD. antidepressants 14. Phenobarbital will increase the liver metabolism of _______ to decrease its effectiveness.A. warfarinB. ibuprofenC. acetaminophenD. alcohol 15. Which of the following drugs can erythromycin interact with to cause nausea, headache, and blurredvision?A. Fluoetine (Prozac)B. TegretolC. Tolbutamide (Orinase)D. Penicillin VK 16. Alcohol should not be taken with any drug containing _______ because of the chance of liver toicity.A. aluminum saltsB. MotrinC. acetaminophenD. calcium 17. When taken simultaneously with tetracycline, which of the following will prevent the absorption oftetracycline into the bloodstream?A. TheophyllineB. ErythromycinC.
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