While working on an adenovirus vaccine you perform complement fixation assays to dete Show more Question VII.
While working on an adenovirus vaccine you perform complement fixation assays to dete Show more Question VII.
While working on an adenovirus vaccine you perform complement fixation assays to determine semiquantitatively the titers of anti-viral antibody in the serum of subjects following vaccination. You are using the typical version of CFT in which you add a standard amount of viral antigen and complement to serial dilutions of the subjects sera in which complement was heat-inactivated and then adding sRBC. Your results for three subjects are shown below: Based on these results assess each subsequent statement (56-62) as either factually correct (= true) or incorrect (= false)]: 56. Subject #1 has probably more anti-viral antibody than #2. 57. Subject #1 has probably less anti-viral antibody than #2. 58. Subject #1 has probably more anti-viral antibody than #3. 59. Subject #1 has probably less anti-viral antibody than #3. 60. Subject #2 has probably more anti-viral antibody than #3. 61. Subject #2 has less anti-viral antibody than #3. 62. None of the above 6 statements (56-61) is a valid conclusion. Show less
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